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Jing Liu, MB, PhD

Assistant Research Professor, Physiology
Research Interests

I have broad interests in vascular biology, metabolism, and renal physiology. Prior research experience was dedicated to understanding the roles of lipoproteins in atherosclerosis and aneurysm, microRNA-mediated regulation of vascular remodeling and metabolism, and molecular and cellular mechanisms of renal physiology and blood pressure control. Building on this expertise, my current efforts are devoted to investigating the causal effects of “forever chemicals” per- and polyfluoroalkyl substances (PFAS) in 1) dyslipidemia and macrovascular diseases including atherosclerosis and aneurysm; 2) hypertension and microvascular dysfunction; and 3) renal dysfunction and chronic kidney disease.

Publication Highlights
Liu J*, Qiu Q, Klemens CA, Vineetha Garimella, Huang J, Perera NLD, McDonough CA, Post CM, Lawrence BP, Le TH, Li C, Liang M, Wu JO*. Per- and Poly-fluoroalkyl Substances Promotes Salt Sensitive Hypertension by Upregulating Epithelial Sodium Channel – The First Experimental Evidence Supporting Causality. bioRxiv. 2025 Sep 21:2025.09.19677469. *Corresponding Author.

Liu J, Brosius III FC, Wu JO. Is β-Hydroxybutyrate a Magic Pill in Chronic Kidney Disease? Kidney360. 2025 Jul 31;6(7):1055-1057.

Liu J, Davies S, Wu JO. Profibrotic MAIT17 Cells in Peritoneal Fibrosis – A New Kid on the Block? Journal of American Society of Nephrology. 2025 Jun 1;36(6):1002-1004.

Liu J, Wu J. The Pathogenesis and Impact of Arterial Stiffening in Hypertension. American Journal of Hypertension. 2024 Mar 15;37(4):241-247.

Liu J, Liu Y, Wang F, Liang M. miR-204: Molecular Regulation and Role in Cardiovascular and Renal Diseases. Hypertension. 2021 Aug;78(2):270-281.

Cheng Y, Wang D, Wang F, Liu J, Huang B, Baker MA, Yin J, Wu R, Liu X, Regner KR, Usa K, Liu Y, Zhang C, Dong L, Geurts AM, Wang N, Miller SS, He Y, Liang M. Endogenous miR-204 protects the kidney against chronic injury in hypertension and diabetes. Journal of American Society of Nephrology 2020 Jul;31(7):1539-1554.

Liu J, Lu H, Moorleghen JJ, Howatt DA, Balakrishnan A, Daugherty A. Hypercholesterolemia accelerates both the initiation and progression of angiotensin II-induced abdominal aortic aneurysms. Annals of Vascular Medicine and Research. 2020 Jan; 7(1): 1099.

Liu J, Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Sorci-Thomas M, Cassis LA, Daugherty A. Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice. Arteriosclerosis, Thrombosis, and Vascular Biololgy. 2015 Aug; 35(8): 1826-34.

Complete List of Published Work in MyBibliography

Degrees

  • 2021 MB, Peking University Health Science Center, Beijing, China
  • 2015 PhD, Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY
  • 2018 Postdoctoral Fellow, University of Iowa, Iowa City, IA
  • 2021 Postdoctoral Fellow, Medical College of Wisconsin, Milwaukee, WI