Ronald M. Lynch, PhD

Professor, Physiology
Associate Professor Pharmacology
Professor BIO5 Institute
Director Aribi Institute
Professor Biomedical Engineering
Professor Physiological Sciences - GIDP
Associate Director Shared Resources, University of Arizona Cancer Center
Research Interests

-cells of the pancreas secrete insulin to maintain blood glucose within a narrow range. In type 1 Diabetes these cells are lost causing blood glucose to widely fluctuate. Our work focuses on approaches to diagnose -cell density and drug treatments to protect them. We also develop technologies that provide insulin to patients using biological surrogates within devices that can be inserted into patients.

-cells of the pancreas secrete insulin to maintain blood glucose within a narrow range. In type 1 Diabetes these cells are lost causing blood glucose to widely fluctuate. Our work focuses on approaches
to diagnose -cell density and drug treatments to protect them. We also develop technologies that provide insulin to patients using biological surrogates within devices that can be inserted into patients. 

Degree(s)

  • 1978 BS Chemistry and Biology - University of Miami
  • 1984 PhD Physiology and Biophysics - University of Cincinnati
  • 1984 Post-Doctoral - Laboratory of Kidney and Electrolyte Metabolism
Publication Highlights

Hart, N.J., C.S. Weber, K.K. Papas, S. Limesand, J. Vagner, and R.M. Lynch (2019) Modulation of β-cellsignaling and insulin secretion with a synthetic bivalent ligand composed of Glucagon like peptide-1linked to Glibenclamide. Am. J. Physiol. Cell Physiol. 316:C48-C56. PMID: 30404557

Lynch, R.M, L.S. Tompkins, H.L. Brooks, A.A. Dunn-Meynell and B.E. Levin (2000) Localization ofglucokinase gene expression in the rat brain. Diabetes 49 (5): 693-700.

Carrington, W.A., R.M. Lynch, E.D.W. Moore, K.E. Fogarty and F.S. Fay (1995) Super-resolution 3-dimensional images of fluorescence in cells with minimal light exposure. SCIENCE 268: 1483-1487.